{"id":892,"date":"2025-04-28T13:15:30","date_gmt":"2025-04-28T04:15:30","guid":{"rendered":"https:\/\/diid.kr\/?p=892"},"modified":"2025-04-28T14:21:38","modified_gmt":"2025-04-28T05:21:38","slug":"kaist-%ed%8c%8c%ed%82%a8%ec%8a%a8%eb%b3%91-%ec%b9%98%eb%a3%8c%ec%97%90-%ec%83%88-%ea%b8%b8-%ec%97%b4%eb%8b%a4rna-%ed%8e%b8%ec%a7%91-%ed%9a%a8%ec%86%8c-%ec%97%90%ec%9d%b4%eb%8b%a4","status":"publish","type":"post","link":"https:\/\/diid.kr\/?p=892","title":{"rendered":"KAIST, \ud30c\ud0a8\uc2a8\ubcd1 \uce58\ub8cc\uc5d0 \uc0c8 \uae38 \uc5f4\ub2e4\u2026RNA \ud3b8\uc9d1 \ud6a8\uc18c \u2018\uc5d0\uc774\ub2e4\uc6d0\u2019 \uc138\uacc4 \ucd5c\ucd08 \uaddc\uba85"},"content":{"rendered":"<figure id=\"attachment_895\" aria-describedby=\"caption-attachment-895\" style=\"width: 700px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-895\" src=\"https:\/\/diid.kr\/wp-content\/uploads\/2025\/04\/2-e1745817573465.png\" alt=\"\uc5b4\ub450\uc6b4 \uc9c8\uac10 \ubc30\uacbd \uc704\uc5d0 \ubd80\ub4dc\ub7fd\uac8c \ube5b\ub098\ub294 \uc8fc\ud669\uc0c9 RNA \uc774\uc911 \ub098\uc120 \uad6c\uc870\uac00 \uc911\uc2ec\uc5d0 \ubc30\uce58\ub418\uc5b4 \uc788\ub2e4. \ub465\uae00\uace0 \ub9e4\ub044\ub7fd\uac8c \ud45c\ud604\ub41c \uc774\uc911 \ub098\uc120\uc740 \uc8fc\ubcc0\uc758 \uc740\uc740\ud55c \ube5b\uacfc \uc5b4\uc6b0\ub7ec\uc838 \uc2e0\ube44\ub86d\uace0 \ucd08\ud604\uc2e4\uc801\uc778 \ubd84\uc704\uae30\ub97c \uc790\uc544\ub0b8\ub2e4.\" width=\"700\" height=\"700\" \/><figcaption id=\"caption-attachment-895\" class=\"wp-caption-text\">\ube5b\ub098\ub294 RNA \uc774\uc911 \ub098\uc120, \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc804\ub7b5\uc758 \uc2dc\uc791\uc744 \uc0c1\uc9d5\ud558\ub2e4<\/figcaption><\/figure>\n<h3 data-start=\"160\" data-end=\"203\"><strong>\uc804 \uc138\uacc4 1\ucc9c\ub9cc \ud658\uc790\uc5d0\uac8c \ud76c\ub9dd\u2026\u201c\uc5fc\uc99d \uc870\uc808 \ud1b5\ud55c \uc2e0\uacbd\uc138\ud3ec \ubcf4\ud638 \uac00\ub2a5\uc131\u201d<\/strong><\/h3>\n<p class=\"\" data-start=\"205\" data-end=\"344\">\ud30c\ud0a8\uc2a8\ubcd1 \ud658\uc790\ub4e4\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc774 \ub420 \uc218 \uc788\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \uad6d\ub0b4 \uc5f0\uad6c\uc9c4\uc5d0 \uc758\ud574 \uc81c\uc2dc\ub410\ub2e4. KAIST \ucd5c\ubbfc\uc774 \uad50\uc218 \uc5f0\uad6c\ud300\uc740 \ub1cc \uba74\uc5ed \ubc18\uc751\uc744 \uc870\uc808\ud558\ub294 RNA \ud3b8\uc9d1 \ud6a8\uc18c\ub97c \uc138\uacc4 \ucd5c\ucd08\ub85c \ubc1c\uacac\ud558\uace0, \uc774\ub97c \uae30\ubc18\uc73c\ub85c \ud30c\ud0a8\uc2a8\ubcd1 \uce58\ub8cc\uc758 \uc804\ud600 \uc0c8\ub85c\uc6b4 \uc804\ub7b5\uc744 \uc81c\uc2dc\ud588\ub2e4.<\/p>\n<h3><strong>RNA \ud3b8\uc9d1 \ud6a8\uc18c \u2018\uc5d0\uc774\ub2e4\uc6d0\u2019\u2026\ud30c\ud0a8\uc2a8\ubcd1 \uc9c4\ud589 \uc870\uc808 \uc5f4\uc1e0 \ub420\uae4c<\/strong><\/h3>\n<p class=\"\" data-start=\"389\" data-end=\"583\">KAIST \ub1cc\uc778\uc9c0\uacfc\ud559\uacfc \ucd5c\ubbfc\uc774 \uad50\uc218\ud300\uc740 \uc601\uad6d UCL \uad6d\ub9bd\uc2e0\uacbd\uc804\ubb38\ubcd1\uc6d0, \ud504\ub79c\uc2dc\uc2a4 \ud06c\ub9ad \uc5f0\uad6c\uc18c\uc640\uc758 \uacf5\ub3d9 \uc5f0\uad6c\ub97c \ud1b5\ud574, \ub1cc \uba74\uc5ed\uc138\ud3ec\uc778 \uad50\uc138\ud3ec(astrocyte)\uc758 \uc5fc\uc99d \ubc18\uc751\uc744 \uc870\uc808\ud558\ub294 RNA \ud3b8\uc9d1 \ud6a8\uc18c &#8216;\uc5d0\uc774\ub2e4\uc6d0(ADAR1)&#8217;\uc758 \uc5ed\ud560\uc744 \uaddc\uba85\ud588\ub2e4. \uc5f0\uad6c \uacb0\uacfc\ub294 \uad6d\uc81c \ud559\uc220\uc9c0 \u2018\uc0ac\uc774\uc5b8\uc2a4 \uc5b4\ub4dc\ubc34\uc2a4\ub4dc(Science Advances)\u2019 4\uc6d4\ud638\uc5d0 \uac8c\uc7ac\ub410\ub2e4.<\/p>\n<p class=\"\" data-start=\"585\" data-end=\"767\">\uc5f0\uad6c\ud300\uc740 \ud30c\ud0a8\uc2a8\ubcd1 \ud658\uc790\uc5d0\uac8c\uc11c \uc720\ub798\ud55c \uc904\uae30\uc138\ud3ec\ub97c \ud65c\uc6a9\ud574 \ub1cc\uc138\ud3ec \ubaa8\ub378\uc744 \uc81c\uc791\ud558\uace0, \ubcd1\ub9ac \ub2e8\ubc31\uc9c8\ub85c \uc54c\ub824\uc9c4 \uc54c\ud30c\uc2dc\ub274\ud074\ub808\uc778(\u03b1-synuclein) \uc751\uc9d1\uccb4\ub97c \uc8fc\uc785\ud574 \uc5fc\uc99d \ubc18\uc751\uc744 \ubd84\uc11d\ud588\ub2e4. \uadf8 \uacb0\uacfc, \uc54c\ud30c\uc2dc\ub274\ud074\ub808\uc778 \ub2e8\ub7c9\uccb4(oligomer)\uac00 \uad50\uc138\ud3ec \ub0b4 \uba74\uc5ed \uc2e0\ud638\ub97c \ud65c\uc131\ud654\uc2dc\ud0a4\uba74\uc11c \uc5d0\uc774\ub2e4\uc6d0\uc758 \ube44\uc815\uc0c1\uc801 \ubc1c\ud604\uc744 \uc720\ub3c4\ud558\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n<p class=\"\" data-start=\"769\" data-end=\"917\">\ud2b9\ud788 \uc5d0\uc774\ub2e4\uc6d0\uc774 \uc218\ud589\ud558\ub294 \u2018A-to-I RNA \ud3b8\uc9d1\u2019\uc774 \uc815\uc0c1\uc801\uc778 \uc720\uc804\uc790 \uc870\uc808\uc774 \uc544\ub2cc, \uc5fc\uc99d \uc720\uc804\uc790\uc5d0 \uc9d1\uc911\ub418\uc5b4 \uc788\ub294 \ube44\uc815\uc0c1 \ud328\ud134\uc744 \ubcf4\uc774\ub294 \uac83\uc774 \ubc1d\ud600\uc84c\ub2e4. \uc774\ub294 \ud658\uc790 \uc720\ub798 \uc138\ud3ec \ubaa8\ub378\ubfd0 \uc544\ub2c8\ub77c, \uc2e4\uc81c \ud30c\ud0a8\uc2a8\ubcd1 \ud658\uc790 \ub1cc \uc870\uc9c1\uc5d0\uc11c\ub3c4 \ub3d9\uc77c\ud558\uac8c \uad00\ucc30\ub418\uc5b4 \uc2e0\ub8b0\ub3c4\ub97c \ub192\uc600\ub2e4.<\/p>\n<h3 data-start=\"919\" data-end=\"955\"><strong>RNA \ud3b8\uc9d1 \uc774\uc0c1, \ub9cc\uc131 \uc5fc\uc99d\uacfc \uc2e0\uacbd\uc138\ud3ec \ub3c5\uc131 \uc720\ubc1c<\/strong><\/h3>\n<p class=\"\" data-start=\"957\" data-end=\"1056\">\ucd5c \uad50\uc218\ud300\uc740 \uc774 \uacfc\uc815\uc744 \ud1b5\ud574 RNA \ud3b8\uc9d1 \uc870\uc808 \uc774\uc0c1\uc774 \uad50\uc138\ud3ec\uc758 \ub9cc\uc131 \uc5fc\uc99d\uc744 \uc77c\uc73c\ud0a4\uace0, \uacb0\uad6d \uc2e0\uacbd\uc138\ud3ec \uc190\uc0c1\uacfc \ud30c\ud0a8\uc2a8\ubcd1 \ubcd1\ub9ac \uc9c4\ud589\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc74c\uc744 \uc9c1\uc811 \uc785\uc99d\ud588\ub2e4.<\/p>\n<p class=\"\" data-start=\"1058\" data-end=\"1237\">\uae30\uc874\uc5d0\ub294 \ub2e8\ubc31\uc9c8 \uc751\uc9d1 \ud604\uc0c1\uc774 \uc2e0\uacbd\uc138\ud3ec \ud30c\uad34\uc758 \uc8fc\uc694 \uc6d0\uc778\uc73c\ub85c \uc9c0\ubaa9\ub410\uc9c0\ub9cc, \uc774\ubc88 \uc5f0\uad6c\ub294 RNA \ud3b8\uc9d1 \uc774\uc0c1\uc774 \uc5fc\uc99d\uc744 \ub9e4\uac1c\ud558\ub294 \ud575\uc2ec \uae30\uc804\uc784\uc744 \ubc1d\ud600\ub0c8\ub2e4\ub294 \ub370 \uc758\ubbf8\uac00 \ud06c\ub2e4. \ud2b9\ud788, \uc5d0\uc774\ub2e4\uc6d0\uc774 \ud30c\ud0a8\uc2a8\ubcd1 \uce58\ub8cc\uc758 \uc0c8\ub85c\uc6b4 \ud0c0\uae43 \uc720\uc804\uc790\uac00 \ub420 \uc218 \uc788\ub2e4\ub294 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud574 \uc2e0\uacbd\uc5fc\uc99d \uae30\ubc18 \uce58\ub8cc\uc81c \uac1c\ubc1c\uc758 \ubc29\ud5a5\uc744 \uc644\uc804\ud788 \uc0c8\ub86d\uac8c \uc5f4\uc5c8\ub2e4.<\/p>\n<p class=\"\" data-start=\"1239\" data-end=\"1353\">\ucd5c\ubbfc\uc774 \uad50\uc218\ub294 &#8220;\uc774\ubc88 \uc5f0\uad6c\ub294 \ud30c\ud0a8\uc2a8\ubcd1\uc758 \ubc1c\ubcd1\uacfc \uc9c4\ud589\uc744 RNA \ud3b8\uc9d1\uc774\ub77c\ub294 \uc0c8\ub85c\uc6b4 \uad00\uc810\uc5d0\uc11c \uc774\ud574\ud560 \uc218 \uc788\ub3c4\ub85d \ud588\ub2e4&#8221;\uba70 &#8220;RNA \ud3b8\uc9d1 \uae30\uc220\uc740 \ud5a5\ud6c4 \uc2e0\uacbd\uc5fc\uc99d \uce58\ub8cc\uc81c \uac1c\ubc1c\uc5d0 \uc911\uc694\ud55c \uc804\ud658\uc810\uc774 \ub420 \uac83&#8221;\uc774\ub77c\uace0 \uac15\uc870\ud588\ub2e4.<\/p>\n<h3><strong>\uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc804\ub7b5, \ud658\uc790\ub4e4\uc758 \uc0b6 \ubc14\uafc0\uae4c<\/strong><\/h3>\n<p class=\"\" data-start=\"1386\" data-end=\"1507\">\ud604\uc7ac \ud30c\ud0a8\uc2a8\ubcd1\uc740 \uadfc\ubcf8\uc801 \uce58\ub8cc\ubc95\uc774 \uc5c6\ub294 \uc0c1\ud0dc\ub85c, \uc99d\uc0c1 \uc644\ud654\uc5d0 \uc9d1\uc911\ud55c \uc57d\ubb3c \uc694\ubc95\uc5d0 \uc758\uc874\ud558\uace0 \uc788\ub2e4. \uadf8\ub7ec\ub098 \uc774\ubc88 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc5fc\uc99d \ubc18\uc751\uc744 \uc870\uc808\ud568\uc73c\ub85c\uc368 \uc9c8\ubcd1\uc758 \uc9c4\ud589\uc744 \ub9c9\uac70\ub098 \uc9c0\uc5f0\uc2dc\ud0a4\ub294 \uc0c8\ub85c\uc6b4 \uc811\uadfc\ubc95\uc774 \uac00\ub2a5\ud560 \uac83\uc73c\ub85c \uae30\ub300\ub41c\ub2e4.<\/p>\n<p class=\"\" data-start=\"1509\" data-end=\"1593\">\uc804 \uc138\uacc4 \uc57d 1\ucc9c\ub9cc \uba85 \uc774\uc0c1\uc758 \ud658\uc790\ub4e4\uc5d0\uac8c \uc788\uc5b4 \uc774\ubc88 \ubc1c\uacac\uc740 \ub2e8\uc21c\ud55c \uacfc\ud559\uc801 \uc131\ucde8\ub97c \ub118\uc5b4, \uc0b6\uc758 \uc9c8\uc744 \ubcc0\ud654\uc2dc\ud0ac \uc218 \uc788\ub294 \ud604\uc2e4\uc801 \ud76c\ub9dd\uc774 \ub420 \uc218 \uc788\ub2e4.<\/p>\n<p class=\"\" data-start=\"1595\" data-end=\"1694\">KAIST \uc5f0\uad6c\ud300\uc740 \uc55e\uc73c\ub85c \uc5d0\uc774\ub2e4\uc6d0\uc744 \ud45c\uc801\ud558\ub294 \uad6c\uccb4\uc801 \uce58\ub8cc\uc81c \uac1c\ubc1c \uc5f0\uad6c\ub97c \uc774\uc5b4\uac08 \uacc4\ud68d\uc774\uba70, RNA \ud3b8\uc9d1 \uae30\uc220\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \ucc28\uc138\ub300 \uc2e0\uacbd\uc9c8\ud658 \uce58\ub8cc\ubc95\uc758 \uac1c\ubc1c \uac00\ub2a5\uc131\ub3c4 \uc81c\uc2dc\ud558\uace0 \uc788\ub2e4.<\/p>\n<p data-start=\"1595\" data-end=\"1694\">\n<p data-start=\"1595\" data-end=\"1694\">\n<p data-start=\"1595\" data-end=\"1694\"><strong>\uc774\uae30\ud6c8 \uae30\uc790 (gihu<\/strong><strong>n.lee@diid.kr)<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\uc804 \uc138\uacc4 1\ucc9c\ub9cc \ud658\uc790\uc5d0\uac8c \ud76c\ub9dd\u2026\u201c\uc5fc\uc99d \uc870\uc808 \ud1b5\ud55c \uc2e0\uacbd\uc138\ud3ec \ubcf4\ud638 \uac00\ub2a5\uc131\u201d \ud30c\ud0a8\uc2a8\ubcd1 \ud658\uc790\ub4e4\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc774 \ub420 \uc218 \uc788\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \uad6d\ub0b4 \uc5f0\uad6c\uc9c4\uc5d0 \uc758\ud574 \uc81c\uc2dc\ub410\ub2e4. KAIST \ucd5c\ubbfc\uc774 \uad50\uc218 \uc5f0\uad6c\ud300\uc740 \ub1cc \uba74\uc5ed \ubc18\uc751\uc744 \uc870\uc808\ud558\ub294 RNA \ud3b8\uc9d1 \ud6a8\uc18c\ub97c \uc138\uacc4 \ucd5c\ucd08\ub85c \ubc1c\uacac\ud558\uace0, \uc774\ub97c \uae30\ubc18\uc73c\ub85c \ud30c\ud0a8\uc2a8\ubcd1 \uce58\ub8cc\uc758 \uc804\ud600 \uc0c8\ub85c\uc6b4 \uc804\ub7b5\uc744 \uc81c\uc2dc\ud588\ub2e4. RNA \ud3b8\uc9d1 \ud6a8\uc18c \u2018\uc5d0\uc774\ub2e4\uc6d0\u2019\u2026\ud30c\ud0a8\uc2a8\ubcd1 \uc9c4\ud589 \uc870\uc808 \uc5f4\uc1e0 \ub420\uae4c KAIST \ub1cc\uc778\uc9c0\uacfc\ud559\uacfc [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":895,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[119,121,128,124,126,123,127,125,122,120],"class_list":["post-892","post","type-post","status-publish","format-standard","has-post-thumbnail","category-news","tag-kaist","tag-rna-","tag-science-advances","tag-124","tag-126","tag-123","tag-127","tag-125","tag-122","tag-120"],"_links":{"self":[{"href":"https:\/\/diid.kr\/index.php?rest_route=\/wp\/v2\/posts\/892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diid.kr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diid.kr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diid.kr\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/diid.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=892"}],"version-history":[{"count":2,"href":"https:\/\/diid.kr\/index.php?rest_route=\/wp\/v2\/posts\/892\/revisions"}],"predecessor-version":[{"id":897,"href":"https:\/\/diid.kr\/index.php?rest_route=\/wp\/v2\/posts\/892\/revisions\/897"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diid.kr\/index.php?rest_route=\/wp\/v2\/media\/895"}],"wp:attachment":[{"href":"https:\/\/diid.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=892"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diid.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=892"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diid.kr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}